Sephardic & Iranian Jewish Genetic Diseases
Sephardic/Oriental Jewry and Genetic Diseases:
For the many purposes of identifying genetic disorders, Sephardic and Oriental Jews can be defined as any Jews who are not of Ashkenazi origin. However, this is a varied group with ancestors from Persia (Iran), Yemen, North Africa (e.g., Morocco, Tunisia), Spain, Italy, the Balkans, Iraq, India, etc. These distinc subgroups of Jews evolved in the Middle East, Mediterranean and Far East with some disorders unique to each subpopulation.


Wolman Disease

Usher Syndrome (Type 2)

Pseudocholinesterase deficiency

Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency


Congenital Hypoaldosteronism

Polyglandular deficiency

Familial Mediterranean Fever (FMF)

Glycogen Storage Disease (Type III)